HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-N-methylacetamide → 2-{6-Chloro-3-[4-(2-methoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-N-methyl-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-N-methylacetamide | HCID 66773 | — |
| Reactant | (6-Chloro-1H-indol-3-yl)[4-(2-methoxyphenyl)piperidin-1-yl]methanone | HCID 59429632 | — |
| Product | 2-{6-Chloro-3-[4-(2-methoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-N-methyl-acetamide | HCID 16062960 | — |
Reaction Steps
Following general procedure II, the alkylation of (6-Chloro-1H-indol-3-yl)-[4-(2-methoxy-phenyl)-piperidin-1-yl]-methanone (preparation described herein), with (commercially available) 2-chloro-N-methyl-acetamide gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07781436B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-7c56d038b4ce4f4bb041f0bbfb9a64e8 |
| Source note | uspto-grants-2010_08 |