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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 505174Generated: October 26, 2026

1-(2-Fluorophenyl)piperazine → (6-Chloro-1H-indol-3-yl)[4-(2-fluorophenyl)piperazin-1-yl]methanone

https://huagongshe.com/reaction/505174

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Fluorophenyl)piperazineHCID 70529—
Reactant6-chloro-1H-indole-3-carboxylic acidHCID 18453235—
Product(6-Chloro-1H-indol-3-yl)[4-(2-fluorophenyl)piperazin-1-yl]methanoneHCID 16061731—

Reaction Steps

Following general procedure I, the coupling of (commercially available) 1-(2-fluoro-phenyl)-piperazine (described herein) with 6-chloro-1H-indole-3-carboxylic acid gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07781436B2
Source datasetuspto-grants-2010_08
ORD IDord-8d549e7cb1484da586544d10e48ed423
Source noteuspto-grants-2010_08