HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 178503328, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 8-Bromo-6-chloro-3,4-dihydro-4-methyl-2(1H)-quinazolinethione | HCID 86608955 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 178503328 | HCID 178503328 | 58.1% |
Reaction Steps
Methyl iodide (0.51 ml, 8.23 mmol) was added to a suspension of 8-bromo-6-chloro-4-methyl-3,4-dihydro-1H-quinazoline-2-thione (800 mg, 2.74 mmol) in acetone (8 ml). The mixture was stirred for 3 hours (r.t.), and the title compound (690 mg, 58%) was isolated from the reaction mixture by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07781441B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-c1c2627ee6814906b551889d526ef8a0 |
| Source note | uspto-grants-2010_08 |