2-Amino-3-nitro-5-p-tolylpyridine → 2,3-Diamino-5-p-tolyl-pyridine

Beteiligte Stoffe

Reaktionsschritte

A solution of 3.25 g of 2-amino-5-(p-tolyl)-3-nitro-pyridine (compound G3) and 325 mg of Pd/C (10%) in 260 ml of methanol is treated with hydrogen under vigorous stirring at room temperature for 18 h. The suspension is filtered with suction through a celite pad. The colorless filtrate is evaporated to dryness to afford 2.63 g of the pure title compound of m.p. 141° C. MS: 200.3 (MH+).

Herkunft & Nachweise