HCID 58758883, compound → HCID 58758884, compound

HRID 505449Notes

Reaction equation

HRID 505449 reaction equation
[C:1]([C:9]1[CH:26]=[C:25]([O:27][CH3:28])[CH:24]=[CH:23][C:10]=1[C:11]([N:13]([CH:20]1[CH2:22][CH2:21]1)[CH2:14][C:15]1[S:16][CH:17]=[CH:18][N:19]=1)=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>O>[CH:20]1([N:13]2[CH:14]([C:15]3[S:16][CH:17]=[CH:18][N:19]=3)[C:1]([OH:8])([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:9]3[C:10](=[CH:23][CH:24]=[C:25]([O:27][CH3:28])[CH:26]=3)[C:11]2=[O:12])[CH2:21][CH2:22]1

Participants

3

Reactant 1

HCID 58758883HCID 58758883, compound

Product 1

HCID 58758884HCID 58758884, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Compound 16 was prepared by cyclization of amide 15 essentially according to the procedure described in Example I, Step E. No spontaneous elimination of water was observed under these conditions.

Sources & evidence

ORD record
ord-c56e467ba180454eadada80f7acc4bc0
Source dataset
uspto-grants-2010_08
Patent number
US07781457B2

Reaction notes

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