HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Fluorocinnamic acid → HCID 68443237, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Fluorocinnamic acid | HCID 98321 | — |
| Edukt | (2S)-2-Amino-3-{3-bromo-4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid methyl ester | HCID 68445645 | — |
| Produkt | HCID 68443237 | HCID 68443237 | 28% |
Reaktionsschritte
Following the procedures described in Example 1, Intermediate 3B was used in place of Intermediate 3A, and α-fluorocinnamic acid was used in place of cinnamic acid to give (2S)-3-{3-bromo-4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)-ethoxy]-phenyl}-2-(2-fluoro-3-phenyl-acryloylamino)-propionic acid as a white solid with the yield of 28% and mp: 243˜245° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07781468B2 |
| Quelldatensatz | uspto-grants-2010_08 |
| ORD ID | ord-bdf3485af665496588696eb5b5cae4ce |
| Quellennotiz | uspto-grants-2010_08 |