4-Pyridin-2-ylbenzaldehyde → (E)-3-[4-(5-Pyrimidinyl)phenyl]-2-propenal

HRID 50567Notes

Reaction equation

HRID 50567 reaction equation
[N:1]1[CH:6]=[C:5]([C:7]2[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=2)[CH:4]=[N:3][CH:2]=1.N1C=CC=CC=1C1C=C[C:24]([CH:25]=[O:26])=CC=1>>[N:1]1[CH:6]=[C:5]([C:7]2[CH:14]=[CH:13][C:10](/[CH:11]=[CH:24]/[CH:25]=[O:26])=[CH:9][CH:8]=2)[CH:4]=[N:3][CH:2]=1

Participants

3

Reactant 2

HCID 15152404-Pyridin-2-ylbenzaldehydeHCID 38612125-(4-Formylphenyl)pyrimidine

Product 1

HCID 22631153(E)-3-[4-(5-Pyrimidinyl)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 31 by substituting 4-(5-pyrimidinyl)-benzaldehyde (prepared as described in Reference Example 25) for the 4-(2-pyridinyl)-benzaldehyde of Reference Example 31. MS 211 (M+H)+.

Sources & evidence

ORD record
ord-17b64bc8f5254ddc8ec0b8a546b69746
Source dataset
uspto-grants-2004_03
Patent number
US06713455B2

Reaction notes

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