化工社化工社 化学情報印刷レポート · 研究参考用
2-Methyl-1,3-thiazole-5-carbaldehyde → Methyl 6-[(2-methyl-1,3-thiazol-5-yl)methylene]-5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methyl-1,3-thiazole-5-carbaldehyde | HCID 13934728 | — |
| 反応物 | Methyl 5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylate | HCID 15309116 | — |
| 生成物 | Methyl 6-[(2-methyl-1,3-thiazol-5-yl)methylene]-5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylate | HCID 66722648 | 60% |
反応手順
The title compound was prepared from 5-oxo-5,6,7,8-tetrahydronaphtalene-2-carboxylic acid methyl ester (396 mg, 1.9 mmol) and 2-methyl-1,3-thiazole-5-carbaldehyde (220 mg, 2.0 mmol) according to Method A3 in 60% yield. ES-MS m/z 314 (M+H)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07781428B2 |
| 出典データセット | uspto-grants-2010_08 |
| ORD ID | ord-bf6eb591ea2a403b8dc84e767570ed52 |
| 出典メモ | uspto-grants-2010_08 |