Methyl Glycolate → HCID 68802139, compound

Participants

Reaction Steps

The title compound was prepared from (±)-(3SR,3aRS)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid, Example 15 and methyl glycolate according to Method E. 1H NMR (400 MHz, CDCl3) δ ppm 1.20-1.69 (m, 7H), 1.72-1.84 (m, 1H), 1.89-2.03 (m, 1H), 2.06-2.20 (m, 1H), 2.26-2.36 (m, 1H), 2.86-2.99 (m, 1H), 3.07-3.18 (m, 1H), 3.49 (ddd, J=13.70, 9.40, 4.83 Hz, 1H), 3.82 (s, 3H), 4.65 (dd, J=9.53, 5.50 Hz, 1H), 4.89 (s, 2H) 7.03 (dd, J=8.73, 2.01 Hz, 1H), 7.31 (d, J=1.88 Hz, 1H), 7.46 (d, J=8.86 Hz, 1H), 7.95-8.01 (m, 2H), 8.17 (d, J=8.86 Hz, 1H). ES-MS m/z 492 (M+H).

Provenance & Evidence