Triethylamine → HCID 68419334, compound

Participants

Reaction Steps

2-(4-Cyclopropyl-1,2,3-thiadiazol-5-ylcarbonylamino)benzoic acid (0.77 g; 2.7 mmols), triethylamine (0.54 g; 5.3 mmols) and 2-chloro-1-methylpyridinium iodide (0.82 g; 3.2 mmols) were dissolved or suspended in THF (15 ml), followed by stirring at room temperature for 10 hours. Subsequently, insoluble materials were removed by filtration, and the filtrate was concentrated under reduced pressure. Crystals thus formed were washed with methanol to obtain 0.63 g of 2-(4-cyclopropyl-1,2,3-thiadiazol-5-yl)-4H-3,1-benzoxazin-4-one.

Provenance & Evidence