Methanol → HCID 59432156, compound

Participants

Reaction Steps

25 g (90.3 mmol) of 2-(4-fluoro-2-trifluoromethylbenzoylamino)but-3-enoic acid were dissolved in methanol, and 9.9 g (82.8 mmol) of thionyl chloride were added dropwise over a period of 30 min. The solution was stirred at RT for three days. Removal of the solvent gave 25.2 g of product (100% of theory) of the title compound as a colorless solid.

Provenance & Evidence