5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid → N-[6-(3-Azabicyclo[3.1.0]hex-3-yl)pyridin-3-yl]-5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxamide

Participants

Reaction Steps

The process is carried out according to the method described in example 2, using 0.15 g (0.52 mmol) of 5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid and 0.1 g (0.57 mmol) of 2-(3-azabicyclo[3.1.0]hex-3-yl)-5-aminopyridine, prepared in step 12.2. 0.17 g of the expected product is thus isolated.

Provenance & Evidence