HRID50666

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID30630

Brofoxine

C10H10BrNO2

HCID74299

Benzeneboronic acid, p-chloro-

C6H6BClO2

PRODUCTS

生成物

结构：CC1(C)OC(=O)Nc2ccc(-c3ccc(Cl)cc3)cc21

HCID9795931

6-(4-chlorophenyl)-4,4-dimethyl-1H-3,1-benzoxazin-2-one

C16H14ClNO2

PROCEDURE

实验过程

Prepared according to Procedure A from 6-bromo-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one and 4-chlorophenyl boronic acid. White solid: mp 255-257° C.; 1H-NMR (DMSO-d6) δ 10.3 (s, 1H), 7.7 (d, 2H, J=8.52 Hz), 7.55 (m, 2H), 7.5 (d, 2H, J=8.52 Hz), 6.96 (d, 1H, J=8.52 Hz), 1.7 (s, 6H); MS (ESI) m/z 288 ([M+H]+, 70%); Anal. Calc. For C16H14ClNO2: C, 66.79; H, 4.90; N, 4.87. Found: C, 66.34; H, 4.76; N, 4.75.

WORKUP

后处理

customPrepared