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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506695Generated: November 4, 2026

Benzyl Bromide → HCID 16679222, compound

https://huagongshe.com/reaction/506695

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
ReactantSodium hydrideHCID 24758—
Reactant8-(1-isopropylpiperidin-4-yloxy)-3,4-dihydropyrazino[1,2-a]indol-1(2H)-oneHCID 16679518—
ProductHCID 16679222HCID 1667922266%

Reaction Steps

The title compound was synthesized in analogy to example 17, from 8-(1-isopropyl-piperidin-4-yloxy)-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (example 1), sodium hydride and benzyl bromide, to give the desired product as a white solid (66%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786109B2
Source datasetuspto-grants-2010_08
ORD IDord-928dcba27ebf4cee80d1a1d905b52812
Source noteuspto-grants-2010_08