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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506740Generated: November 2, 2026

N-bromobutanimide → HCID 16679028, compound

https://huagongshe.com/reaction/506740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-bromobutanimideHCID 67184—
Reactant(R)-8-(1-isopropylpiperidin-4-yloxy)-4-methyl-3,4-dihydropyrazino[1,2-a]indol-1(2H)-oneHCID 16679612—
ProductHCID 16679028HCID 1667902869%

Reaction Steps

The title compound was synthesized in analogy to example 82, from (R)-8-(1-isopropyl-piperidin-4-yloxy)-4-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (example 8) and N-bromosuccinimide, to give the desired product as a light yellow oil (69%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786109B2
Source datasetuspto-grants-2010_08
ORD IDord-1c3e7ce42ee946988207f404a7791e5f
Source noteuspto-grants-2010_08