反应详情

The suspension consistent of 0.20 g (0.68 mmol) 7-benzyloxy-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one and 30 μg palladium on activated charcoal (10% Pd; commercially available) in 2 mL formic acid was hydrogenated at room temperature at 1.5 bar for 3 hours. The reaction mixture was filtered over Dicalite Speed Plus® (Aldrich), the filter cake was washed with formic acid and the volatile components were evaporated at a rotary evaporator. The residue was stirred in 3 mL ethyl acetate, filtered and the light brown product (65%) was dried under high vacuum.

1. filtrationThe reaction mixture was filtered over Dicalite
2. washPlus® (Aldrich), the filter cake was washed with formic acid
3. customthe volatile components were evaporated at a rotary evaporator
4. filtrationfiltered
5. dry with materialthe light brown product (65%) was dried under high vacuum