HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68468453, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68467065 | HCID 68467065 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68468453 | HCID 68468453 | — |
Reaction Steps
The product is prepared by following the procedure described in example 51 starting with 0.115 g of tert-butyl 4-({[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}methyl)piperidine-1-carboxylate instead of the tert-butyl (2-{[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}ethyl)carbamate used in example 51 and 1.3 cm3 of 5N hydrochloric acid in dioxane. 0.101 g of [2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]-piperidin-4-ylmethylamine hydrochloride is obtained with the following characteristics:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07786114B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-817d8613c5364ff2a12bb69eeccf0a69 |
| Source note | uspto-grants-2010_08 |