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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506821Generated: October 30, 2026

Hydrochloric Acid → HCID 68468453, compound

https://huagongshe.com/reaction/506821

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 68467065HCID 68467065—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 68468453HCID 68468453—

Reaction Steps

The product is prepared by following the procedure described in example 51 starting with 0.115 g of tert-butyl 4-({[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}methyl)piperidine-1-carboxylate instead of the tert-butyl (2-{[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}ethyl)carbamate used in example 51 and 1.3 cm3 of 5N hydrochloric acid in dioxane. 0.101 g of [2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]-piperidin-4-ylmethylamine hydrochloride is obtained with the following characteristics:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786114B2
Source datasetuspto-grants-2010_08
ORD IDord-817d8613c5364ff2a12bb69eeccf0a69
Source noteuspto-grants-2010_08