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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506824Generated: November 4, 2026

Hydrochloric Acid → HCID 68466478, compound

https://huagongshe.com/reaction/506824

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 69480303HCID 69480303—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 68466478HCID 68466478—

Reaction Steps

The product is prepared by following the procedure described in example 51, starting with 0.120 g of tert-butyl (4-{[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}cyclohexyl)-carbamate instead of the tert-butyl (2-{[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}ethyl)carbamate used in example 51 and 2 cm3 of 5N hydrochloric acid in dioxane. 0.133 g of N-[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]cyclohexane-1,4-diamine hydrochloride is obtained with the following characteristics:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786114B2
Source datasetuspto-grants-2010_08
ORD IDord-ef412e1a15004aeeb8305b4ffb86d43e
Source noteuspto-grants-2010_08