HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68466478, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 69480303 | HCID 69480303 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68466478 | HCID 68466478 | — |
Reaction Steps
The product is prepared by following the procedure described in example 51, starting with 0.120 g of tert-butyl (4-{[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}cyclohexyl)-carbamate instead of the tert-butyl (2-{[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}ethyl)carbamate used in example 51 and 2 cm3 of 5N hydrochloric acid in dioxane. 0.133 g of N-[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]cyclohexane-1,4-diamine hydrochloride is obtained with the following characteristics:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07786114B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-ef412e1a15004aeeb8305b4ffb86d43e |
| Source note | uspto-grants-2010_08 |