Tert-butyl 3-aminoazetidine-1-carboxylate → HCID 68469678, compound

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Reaction Steps

The product is prepared by following the procedure described in example 52c, starting with 0.3 g of 3-[4-chloromethyl-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridine and 0.253 g of 3-amino-1N-Boc-azetidine instead of the N-Boc-ethylenediamine used in example 52c. 0.203 g of tert-butyl 3-{[2-(5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl]amino}azetidine-1-carboxylate is obtained with the following characteristics:

Provenance & Evidence