1-Bromo-4-chlorobutane → 3-(4-Chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one
Reaction equation
[CH2:1]([CH:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5][C:4]1=[O:12])[CH3:2].Br[CH2:14][CH2:15][CH2:16][CH2:17][Cl:18]>>[Cl:18][CH2:17][CH2:16][CH2:15][CH2:14][C:3]1([CH2:1][CH3:2])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5][C:4]1=[O:12]Participants
3
Procedure
The title compound is prepared according to process E starting from 3-ethyl-1,3-dihydro-2H-indol-2-one and 1-bromo-4-chlorobutane.
Sources & evidence
- ORD record
- ord-59a1d4850996428baf8746802b732bd4
- Source dataset
- uspto-grants-2010_08
- Patent number
- US07786129B2
Reaction notes
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