1-Bromo-4-chlorobutane → 3-(4-Chlorobutyl)-3-ethyl-5-fluoro-1,3-dihydro-2H-indol-2-one

HRID 506894Notes

Reaction equation

HRID 506894 reaction equation
[CH2:1]([CH:3]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([F:12])[CH:10]=2)[NH:5][C:4]1=[O:13])[CH3:2].Br[CH2:15][CH2:16][CH2:17][CH2:18][Cl:19]>>[Cl:19][CH2:18][CH2:17][CH2:16][CH2:15][C:3]1([CH2:1][CH3:2])[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([F:12])[CH:10]=2)[NH:5][C:4]1=[O:13]

Participants

3

Reactant 2

HCID 813641-Bromo-4-chlorobutaneHCID 11367341HCID 11367341, compound

Product 1

HCID 670412173-(4-Chlorobutyl)-3-ethyl-5-fluoro-1,3-dihydro-2H-indol-2-one

Procedure

The title compound is prepared according to process E starting from 3-ethyl-5-fluoro-1,3-dihydro-2H-indol-2-one and 1-bromo-4-chloro-butane.

Sources & evidence

ORD record
ord-63c8f0bf0c2340e38d52e63c9b0f6d69
Source dataset
uspto-grants-2010_08
Patent number
US07786129B2

Reaction notes

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