1-Bromo-4-chlorobutane → 3-(4-Chlorobutyl)-3-ethyl-5-methyl-1,3-dihydro-2H-indol-2-one
Reaction equation
[CH2:1]([CH:3]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([CH3:12])[CH:10]=2)[NH:5][C:4]1=[O:13])[CH3:2].Br[CH2:15][CH2:16][CH2:17][CH2:18][Cl:19]>>[Cl:19][CH2:18][CH2:17][CH2:16][CH2:15][C:3]1([CH2:1][CH3:2])[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([CH3:12])[CH:10]=2)[NH:5][C:4]1=[O:13]Participants
3
Procedure
The title compound is prepared according to process E starting from 3-ethyl-5-methyl-1,3-dihydro-2H-indol-2-one and 1-bromo-4-chloro-butane.
Sources & evidence
- ORD record
- ord-5882a44677d84a88a0ac27c32ee95e9b
- Source dataset
- uspto-grants-2010_08
- Patent number
- US07786129B2
Reaction notes
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