1-(3-Chlorophenyl)piperazine → 3-{4-[4-(3-Chlorophenyl)-piperazin-1-yl]-butyl}-3-isobutyl-1,3-dihydro-2H-indol-2-one monohydrochloride

HRID 506908Notes

Reaction equation

HRID 506908 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([CH2:16][CH:17]([CH3:19])[CH3:18])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]1=[O:15].[Cl:20][C:21]1[CH:22]=[C:23]([N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH:24]=[CH:25][CH:26]=1>>[ClH:1].[Cl:20][C:21]1[CH:22]=[C:23]([N:27]2[CH2:32][CH2:31][N:30]([CH2:2][CH2:3][CH2:4][CH2:5][C:6]3([CH2:16][CH:17]([CH3:19])[CH3:18])[C:14]4[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=4)[NH:8][C:7]3=[O:15])[CH2:29][CH2:28]2)[CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 13551-(3-Chlorophenyl)piperazineHCID 684633823-(4-Chlorobutyl)-3-isobutyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 248541843-{4-[4-(3-Chlorophenyl)-piperazin-1-yl]-butyl}-3-isobutyl-1,3-dihydro-2H-indol-2-one monohydrochloride

Procedure

The title compound is prepared according to process H by applying processing method 2 starting from 3-(4-chlorobutyl)-3-isobutyl-1,3-dihydro-2H-indol-2-one and 1-(3-chlorophenyl)-piperazine.

Sources & evidence

ORD record
ord-47bc5a6a86a64bf3a0d02556cee3719f
Source dataset
uspto-grants-2010_08
Patent number
US07786129B2

Reaction notes

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