1-(3-Chlorophenyl)piperazine → 3-{4-[4-(3-Chlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-5-methyl-1,3-dihydro-2H-indol-2-one

HRID 506911Notes

Reaction equation

HRID 506911 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([CH2:17][CH3:18])[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([CH3:15])[CH:13]=2)[NH:8][C:7]1=[O:16].[Cl:19][C:20]1[CH:21]=[C:22]([N:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH:23]=[CH:24][CH:25]=1>>[Cl:19][C:20]1[CH:21]=[C:22]([N:26]2[CH2:31][CH2:30][N:29]([CH2:2][CH2:3][CH2:4][CH2:5][C:6]3([CH2:17][CH3:18])[C:14]4[C:9](=[CH:10][CH:11]=[C:12]([CH3:15])[CH:13]=4)[NH:8][C:7]3=[O:16])[CH2:28][CH2:27]2)[CH:23]=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 13551-(3-Chlorophenyl)piperazineHCID 684650173-(4-Chlorobutyl)-3-ethyl-5-methyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 684635403-{4-[4-(3-Chlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-5-methyl-1,3-dihydro-2H-indol-2-one

Procedure

The title compound is prepared according to process H by applying processing method 1 starting from 3-(4-chlorobutyl)-3-ethyl-5-methyl-1,3-dihydro-2H-indol-2-one and 1-(3-chloro-phenyl)-piperazine.

Sources & evidence

ORD record
ord-c5ffe9f56a26442d9d6837063e83441d
Source dataset
uspto-grants-2010_08
Patent number
US07786129B2

Reaction notes

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