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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506916Generated: November 2, 2026

1-(4-Chlorophenyl)piperazine → 3-{4-[4-(4-Chlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one

https://huagongshe.com/reaction/506916

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chlorophenyl)piperazineHCID 97478—
Reactant3-(4-Chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-oneHCID 68463623—
Product3-{4-[4-(4-Chlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-oneHCID 24829343—

Reaction Steps

The title compound is prepared according to process H by applying processing method 1 starting from 3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one and 1-(4-chloro-phenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-a9484c6af408471495d23529f9af01c0
Source noteuspto-grants-2010_08