1-(3-Chlorophenyl)piperazine → HCID 24854042, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([F:19])[CH:5]=[C:6]2[C:10]=1[NH:9][C:8](=[O:11])[C:7]2([CH2:14][CH2:15][CH2:16][CH2:17]Cl)[CH2:12][CH3:13].[Cl:20][C:21]1[CH:22]=[C:23]([N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH:24]=[CH:25][CH:26]=1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([F:19])[CH:5]=[C:6]2[C:10]=1[NH:9][C:8](=[O:11])[C:7]2([CH2:14][CH2:15][CH2:16][CH2:17][N:30]1[CH2:29][CH2:28][N:27]([C:23]2[CH:24]=[CH:25][CH:26]=[C:21]([Cl:20])[CH:22]=2)[CH2:32][CH2:31]1)[CH2:12][CH3:13]Participants
3
Procedure
The title compound is prepared according to process H by applying processing method 2 starting from 7-chloro-3-(4-chlorobutyl)-3-ethyl-5-fluoro-1,3-dihydro-2H-indol-2-one and 1-(3-chlorophenyl)-piperazine.
Sources & evidence
- ORD record
- ord-7c249cc74da34cb49023a176e4dadfd8
- Source dataset
- uspto-grants-2010_08
- Patent number
- US07786129B2
Reaction notes
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