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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506919Generated: October 27, 2026

1-(3-Chlorophenyl)piperazine → 5-Chloro-3-{4-[4-(3-chlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one monohydrochloride

https://huagongshe.com/reaction/506919

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Chlorophenyl)piperazineHCID 1355—
Reactant5-chloro-3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-oneHCID 68463816—
Product5-Chloro-3-{4-[4-(3-chlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one monohydrochlorideHCID 24854265—

Reaction Steps

The title compound is prepared according to process H by applying processing method 2 starting from 5-chloro-3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one and 1-(3-chlorophenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-13374a859e924ca5ba394c93ddb4f0a1
Source noteuspto-grants-2010_08