1-(2-Chlorophenyl)piperazine → 3-{5-[4-(2-chlorophenyl)-piperazin-1-yl]-pentyl}-3-ethyl-1,3-dihydro-2H-indol-2-one monohydro-chloride

HRID 506922Notes

Reaction equation

HRID 506922 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]1([CH2:17][CH3:18])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH:9][C:8]1=[O:16].[Cl:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[N:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[ClH:19].[Cl:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[N:26]1[CH2:31][CH2:30][N:29]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]2([CH2:17][CH3:18])[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[NH:9][C:8]2=[O:16])[CH2:28][CH2:27]1

Participants

3

Reactant 2

HCID 4156281-(2-Chlorophenyl)piperazineHCID 684651933-(5-Bromopentyl)-3-ethyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 684673943-{5-[4-(2-chlorophenyl)-piperazin-1-yl]-pentyl}-3-ethyl-1,3-dihydro-2H-indol-2-one monohydro-chloride

Procedure

The title compound is prepared according to process H by applying processing method 2 starting from 3-(5-bromopentyl)-3-ethyl-1,3-dihydro-2H-indol-2-one and 1-(2-chlorophenyl)-piperazine.

Sources & evidence

ORD record
ord-a819048e7e7849dabbf75df884a3120b
Source dataset
uspto-grants-2010_08
Patent number
US07786129B2

Reaction notes

Loading…