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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506925Generated: October 26, 2026

1-(4-Chloro-o-tolyl)piperazine → 3-{4-[4-(4-Chloro-2-methylphenyl)-piperazin-1-yl]-butyl}-3-ethyl-1,3-dihydro-2H-indol-2-one monohydrochloride

https://huagongshe.com/reaction/506925

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chloro-o-tolyl)piperazineHCID 100852—
Reactant3-(4-Chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-oneHCID 67040633—
Product3-{4-[4-(4-Chloro-2-methylphenyl)-piperazin-1-yl]-butyl}-3-ethyl-1,3-dihydro-2H-indol-2-one monohydrochlorideHCID 68464128—

Reaction Steps

The title compound is prepared according to process H by applying processing method 2 starting from 3-(4-chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one and 1-(4-chloro-2-methyl-phenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-8746a43a58d84e629a7ad30eccf01a87
Source noteuspto-grants-2010_08