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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506927Generated: October 27, 2026

3-Chloro-4-fluorophenylpiperazine → 3-{4-[4-(3-Chloro-4-fluorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-1,3-dihydro-2H-indol-2-one

https://huagongshe.com/reaction/506927

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-fluorophenylpiperazineHCID 2779263—
Reactant3-(4-Chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-oneHCID 67040633—
Product3-{4-[4-(3-Chloro-4-fluorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-1,3-dihydro-2H-indol-2-oneHCID 24853955—

Reaction Steps

The title compound is prepared according to process H by applying processing method 1 starting from 3-(4-chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one and 1-(3-chloro-4-fluoro-phenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-3de0b3b8ae0c4bdf9e6ed23224d365e4
Source noteuspto-grants-2010_08