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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506932Generated: October 26, 2026

1-(3-Fluorophenyl)piperazine → 3-Ethyl-3-{4-[4-(3-fluorophenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one monohydro-chloride

https://huagongshe.com/reaction/506932

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Fluorophenyl)piperazineHCID 77418—
Reactant3-(4-Chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-oneHCID 67040633—
Product3-Ethyl-3-{4-[4-(3-fluorophenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one monohydro-chlorideHCID 68467964—

Reaction Steps

The title compound is prepared according to process H by applying processing method 2 starting from 3-(4-chlorobutyl)-3-ethyl-1,3-di-hydro-2H-indol-2-one and 1-(3-fluorophenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-cdce35b5e0dd4accb43eda14c48cd318
Source noteuspto-grants-2010_08