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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506934Generated: October 26, 2026

1-(2,4-Dichlorophenyl)piperazine → 5-Chloro-3-{4-[4-(2,4-dichlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one monohydrochloride

https://huagongshe.com/reaction/506934

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,4-Dichlorophenyl)piperazineHCID 2737527—
Reactant5-chloro-3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-oneHCID 68463816—
Product5-Chloro-3-{4-[4-(2,4-dichlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one monohydrochlorideHCID 68466518—

Reaction Steps

The title compound is prepared according to process H by applying processing method 2 starting from 5-chloro-3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one and 1-(2,4-dichlorophenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-8b1f8b3ef1f04116b64d7c12dc0f9c1f
Source noteuspto-grants-2010_08