1-(3-Chlorophenyl)piperazine → 3-{3-[4-(3-chlorophenyl)-piperazin-1-yl]-propyl}-3-ethyl-1,3-dihydro-2H-indol-2-one

HRID 506935Notes

Reaction equation

HRID 506935 reaction equation
Cl[CH2:2][CH2:3][CH2:4][C:5]1([CH2:15][CH3:16])[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[NH:7][C:6]1=[O:14].[Cl:17][C:18]1[CH:19]=[C:20]([N:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH:21]=[CH:22][CH:23]=1>>[Cl:17][C:18]1[CH:19]=[C:20]([N:24]2[CH2:29][CH2:28][N:27]([CH2:2][CH2:3][CH2:4][C:5]3([CH2:15][CH3:16])[C:13]4[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=4)[NH:7][C:6]3=[O:14])[CH2:26][CH2:25]2)[CH:21]=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 13551-(3-Chlorophenyl)piperazineHCID 684652713-(3-Chloropropyl)-3-ethyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 248541093-{3-[4-(3-chlorophenyl)-piperazin-1-yl]-propyl}-3-ethyl-1,3-dihydro-2H-indol-2-one

Procedure

The title compound is prepared according to process H by applying processing method 1 starting from 3-(3-chloropropyl)-3-ethyl-1,3-dihydro-2H-indol-2-one and 1-(3-chlorophenyl)-piperazine.

Sources & evidence

ORD record
ord-9360ef9b46744cf28039c6f5761a1590
Source dataset
uspto-grants-2010_08
Patent number
US07786129B2

Reaction notes

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