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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506943Generated: November 3, 2026

1-(4-Fluorophenyl)piperazine → 3-Ethyl-6-fluoro-3-{4-[4-(4-fluorophenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one monohydrochloride

https://huagongshe.com/reaction/506943

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)piperazineHCID 75260—
Reactant3-(4-Chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-oneHCID 68463623—
Product3-Ethyl-6-fluoro-3-{4-[4-(4-fluorophenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one monohydrochlorideHCID 68464346—

Reaction Steps

The title compound is prepared according to process H using processing method 2 from 3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one and 1-(4-fluorophenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-67fb46adb2da444daa6c2f6f3b48f629
Source noteuspto-grants-2010_08