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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506947Generated: October 26, 2026

1-(4-Chlorophenyl)piperazine → 5-chloro-3-{4-[4-(4-chlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one

https://huagongshe.com/reaction/506947

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chlorophenyl)piperazineHCID 97478—
Reactant5-chloro-3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-oneHCID 68463816—
Product5-chloro-3-{4-[4-(4-chlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-oneHCID 24854103—

Reaction Steps

The title compound is prepared according to process H by applying processing method 2 from 5-chloro-3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one and 1-(4-chlorophenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-fa3eaaa17b50459eb70afaa7cfce2735
Source noteuspto-grants-2010_08