Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506952Generated: November 2, 2026

1-(4-Fluoro-2-methylphenyl)piperazine → 3-Ethyl-3-{4-[4-(4-fluoro-2-methylphenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one monohydrochloride

https://huagongshe.com/reaction/506952

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluoro-2-methylphenyl)piperazineHCID 18423072—
Reactant3-(4-Chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-oneHCID 67040633—
Product3-Ethyl-3-{4-[4-(4-fluoro-2-methylphenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one monohydrochlorideHCID 68462794—

Reaction Steps

The title compound is prepared according to process H by applying processing method 2 from the starting compounds 3-(4-chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one and 1-(4-fluoro-2-methylphenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-9e59816b89f1460196938fbc1034b476
Source noteuspto-grants-2010_08