5-Chloro-2-thiophenecarboxylic acid → HCID 59434011, compound

HRID 507393Notes

Reaction equation

HRID 507393 reaction equation
[Cl:1][C:2]1[C:3]([CH3:22])=[C:4]([N:8]2[C:12](=[O:13])[CH2:11][N:10]([C:14](=[O:21])[CH2:15][NH:16][CH2:17][CH2:18][O:19][CH3:20])[CH2:9]2)[CH:5]=[CH:6][CH:7]=1.[Cl:23][C:24]1[S:28][C:27]([C:29](O)=[O:30])=[CH:26][CH:25]=1>>[Cl:1][C:2]1[C:3]([CH3:22])=[C:4]([N:8]2[C:12](=[O:13])[CH2:11][N:10]([C:14](=[O:21])[CH2:15][N:16]([CH2:17][CH2:18][O:19][CH3:20])[C:29]([C:27]3[S:28][C:24]([Cl:23])=[CH:25][CH:26]=3)=[O:30])[CH2:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 950485-Chloro-2-thiophenecarboxylic acidHCID 8035647HCID 8035647, compound

Product 1

HCID 59434011HCID 59434011, compound

Procedure

The title compound was prepared by procedure analogous to that described in Example 12 using 3-(3-Chloro-2-methyl-phenyl)-1-[2-(2-methoxy-ethylamino)-acetyl]-imidazolidin-4-one and 5-Chloro-thiophene-2-carboxylic acid. LCMS observed for (M+H)+: 470.2

Sources & evidence

ORD record
ord-f5dd5dc026bb4eb9a21d12a8586f0bf5
Source dataset
uspto-grants-2010_08
Patent number
US07786157B2

Reaction notes

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