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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 507419Generated: October 25, 2026

(2,4-Dimethoxy-phenyl)-acetyl chloride → 2-(2,4-dimethoxy-phenyl)-N-{4-[2-(2-methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-acetamide

https://huagongshe.com/reaction/507419

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2,4-Dimethoxy-phenyl)-acetyl chlorideHCID 23083403—
Reactant3-[2-(4-Amino-phenyl)-2-oxo-ethyl]-2-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-oneHCID 68468184—
Product2-(2,4-dimethoxy-phenyl)-N-{4-[2-(2-methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-acetamideHCID 25255664—

Reaction Steps

Synthesis in analogy to Example 8 starting from 3-[2-(4-amino-phenyl)-2-oxo-ethyl]-2-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-one and (2,4-dimethoxy-phenyl)-acetyl chloride to yield 2-(2,4-dimethoxy-phenyl)-N-{4-[2-(2-methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-acetamide. LC/MS at 254 nm; [M+H] 562; Rt 3.533 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786155B2
Source datasetuspto-grants-2010_08
ORD IDord-8cf9df3d275e46d580b9132473679fcc
Source noteuspto-grants-2010_08