HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-isocyanato-4-nitro- → 1-{4-[2-(2-Methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-3-(4-nitro-phenyl)-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-isocyanato-4-nitro- | HCID 66012 | — |
| Reactant | 3-[2-(4-Amino-phenyl)-2-oxo-ethyl]-2-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-one | HCID 68468184 | — |
| Product | 1-{4-[2-(2-Methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-3-(4-nitro-phenyl)-urea | HCID 68465651 | — |
Reaction Steps
Synthesis in analogy to Example 6 starting from 3-[2-(4-amino-phenyl)-2-oxo-ethyl]-2-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-one and 1-isocyanato-4-nitro-benzene to yield 1-{4-[2-(2-methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-3-(4-nitro-phenyl)-urea. LC/MS at 254 nm; [M+H] 548; Rt 3.601 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07786155B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-b8c88563d8794254b5d3ec72c14e2d62 |
| Source note | uspto-grants-2010_08 |