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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 507422Generated: October 27, 2026

Benzene, 1-isocyanato-4-nitro- → 1-{4-[2-(2-Methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-3-(4-nitro-phenyl)-urea

https://huagongshe.com/reaction/507422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-isocyanato-4-nitro-HCID 66012—
Reactant3-[2-(4-Amino-phenyl)-2-oxo-ethyl]-2-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-oneHCID 68468184—
Product1-{4-[2-(2-Methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-3-(4-nitro-phenyl)-ureaHCID 68465651—

Reaction Steps

Synthesis in analogy to Example 6 starting from 3-[2-(4-amino-phenyl)-2-oxo-ethyl]-2-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-one and 1-isocyanato-4-nitro-benzene to yield 1-{4-[2-(2-methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-3-(4-nitro-phenyl)-urea. LC/MS at 254 nm; [M+H] 548; Rt 3.601 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786155B2
Source datasetuspto-grants-2010_08
ORD IDord-b8c88563d8794254b5d3ec72c14e2d62
Source noteuspto-grants-2010_08