HCID 68461424, compound → HCID 21015128, compound

Participants

Reaction Steps

To a solution of 3 (1.4 g, 3.3 mmol) in 20 mL of pyridine was added 0.1 g DMAP and the mixture was refluxed overnight. After removal of the pyridine, the residue was partitioned between water and ethyl acetate. The organic phase was dried, concentrated and purified by column chromatography on silica gel to afford the pure product (0.5 g, 48%) 1H NMR (400 MHz, CDCl3) δ1.44 (s, 9 H), 2.01 (m, 1 H), 3.19 (m, 1H), 3.77 (d, 3 H), 4.12 (m, 1 H), 5.08-5.16 (m, 3 H).

Provenance & Evidence