HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide dimethyl acetal → (E)-1-(1-benzothiophen-2-yl)-3-(dimethylamino)-2-propen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | 2-Acetylbenzothiophene | HCID 89805 | — |
| Product | (E)-1-(1-benzothiophen-2-yl)-3-(dimethylamino)-2-propen-1-one | HCID 1491723 | 84% |
Reaction Steps
A solution of 1-(benzo[b]thiophen-2-yl)ethanone (1 g) in dimethoxy-N,N-dimethyl-methanamine (10 mL) was refluxed for 6 h and then cooled to rt. The precipitate was filtered and washed with diethyl ether to afford the title compound (1.1 g, 84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07786132B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-f2a5fb2dd3df4d1d81e3f58468b126c1 |
| Source note | uspto-grants-2010_08 |