Propan-2-one--water (1/1) → HCID 60204421, compound

Participants

Reaction Steps

A mixture of (5-(2-(methylthio)pyrimidin-4-yl)thiophen-2-yl)(morpholino)methanone (200 mg) and oxone (2 g) in 60 mL of acetone-water (1:1) was stirred at rt for 24 h. The mixture was concentrated in vacuo to remove the acetone. The white precipitate was filtered, washed with water and dried to give the title compound (183 mg, 83%). MS (M+H)+ 354.

Provenance & Evidence