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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 507595Generated: November 3, 2026

Hydrochloric Acid → HCID 60204495, compound

https://huagongshe.com/reaction/507595

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 60204494HCID 60204494—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 60204495HCID 60204495—

Reaction Steps

A solution of 15 mg (0.024 mmol) of tert-Butyl 2-(3-{4-(5-chlorothiophen-2-yl)-2-[2-(5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)ethylamino]pyrimidin-5-yl}phenylamino)-2-oxoethyl(methyl)carbamate in 1 mL of 1,4-dioxane was treated with 2 mL of a 4 M solution of HCl in 1,4-dioxane and stirred 1 h at rt, then concentrated in vacuo to give the desired product as the hydrochloride salt. MS (M+H)+ 528.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786132B2
Source datasetuspto-grants-2010_08
ORD IDord-09e97389298743c6b249c21178f99898
Source noteuspto-grants-2010_08