HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-fluoropyrimidine → HCID 11705229, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-fluoropyrimidine | HCID 583466 | — |
| Reactant | HCID 19963296 | HCID 19963296 | — |
| Reactant | 1-(2-Aminoethyl)-5,5-dimethylimidazolidine-2,4-dione | HCID 57428804 | — |
| Product | HCID 11705229 | HCID 11705229 | — |
Reaction Steps
5-(4-Fluorobenzyl)thiazole was condensed with 2-chloro-5-fluoropyrimidine and subsequently aminated with 1-(2-aminoethyl)-5,5-dimethylimidazolidine-2,4-dione using procedures analogous to those in Example 24. MS (M+H)+ 459.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07786132B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-fd18b5745b8e408980cee95ed1de47cf |
| Source note | uspto-grants-2010_08 |