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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 507925Generated: November 3, 2026

1,2-Dichloroethane → HCID 178519697, compound

https://huagongshe.com/reaction/507925

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantAcetic AcidHCID 176—
Reactant4-Aminobenzyl alcoholHCID 69331—
Reactant4-Phenyl-1,3-thiazole-2-carbaldehydeHCID 3538814—
SolventHexaneHCID 8058—
ProductHCID 178519697HCID 17851969788.3%

Reaction Steps

A mixture of 4-phenyl-1,3-thiazole-2-carbaldehyde (1.10 g, 5.81 mmol), (4-aminophenyl)methanol (615 mg, 5.0 mmol), acetic acid (0.4 mL) and 1,2-dichloroethane (10 mL) was stirred at room temperature for 30 min. The reaction mixture was diluted with hexane. The precipitated solid was collected by filtration, washed with hexane, and dried to give the title compound (1.30 g, yield 88%) as yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786165B2
Source datasetuspto-grants-2010_08
ORD IDord-c030fbe8d23e465e8c1700c584484805
Source noteuspto-grants-2010_08