HCID 23157290, compound → HCID 23157426, compound

Participants

Reaction Steps

A solution of [4′-(2-ethoxyethoxy)-6-isopropoxybiphenyl-3-yl]methanol (0.90 g, 2.72 mmol) and manganese dioxide (2.7 g, 31.1 mmol) in tetrahydrofuran (40 mL) was stirred at room temperature for 2 hr. The insoluble material was filtered off, and the filtrate was concentrated under reduced pressure. The residue was subjected to silica gel column chromatography (ethyl acetate:hexane=1:19-3:7) to give the title compound (725 mg) as colorless needle crystals. yield 81%.

Provenance & Evidence