Acetic Anhydride → Tert-butyl 3-(4-{[(4'-{2-[acetyl(ethyl)amino]ethoxy}-2',6'-dimethylbiphenyl-3-yl)methyl][(2-nitrophenyl)sulfonyl]amino}-2-fluorophenyl)propanoate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Acetic Anhydride	HCID 7918	—
Edukt	2-(Ethylamino)ethanol	HCID 8072	—
Edukt	Tert-butyl 3-(2-fluoro-4-{[(4'-hydroxy-2',6'-dimethylbiphenyl-3-yl)methyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate	HCID 23157516	—
Produkt	Tert-butyl 3-(4-{[(4'-{2-[acetyl(ethyl)amino]ethoxy}-2',6'-dimethylbiphenyl-3-yl)methyl][(2-nitrophenyl)sulfonyl]amino}-2-fluorophenyl)propanoate	HCID 23157455	—

Reaktionsschritte

In the same manner as in Example 196, the title compound (0.19 g) was obtained as a colorless amorphous powder from tert-butyl 3-(2-fluoro-4-{[(4′-hydroxy-2′,6′-dimethylbiphenyl-3-yl)methyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate, 2-(ethylamino)ethanol and acetic anhydride

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07786165B2
Quelldatensatz	uspto-grants-2010_08
ORD ID	ord-4db2038aa40d4fcf8c810e0707527e77
Quellennotiz	uspto-grants-2010_08