4-(Methylsulfonyl)phenylhydrazine hydrochloride → HCID 11222461, compound

Participants

Reaction Steps

Compound 3a was synthesized in a manner similar to the synthesis of 3b using 4-(methylsulfonyl)phenylhydrazine hydrochloride (10 g, 44.7 mmol) to give 3a (13.6 g, 82% yield) as a white solid. mp 199.4-202.9° C. 1H NMR (300 MHz, DMSO-d6): δ 7.99 (d, J=9 Hz, 2H), 7.58 (d, J=9 Hz, 2H), 7.43-7.38 (m, 3H), 7.34-7.27 (m, 2H), 7.17 (s, 1H), 4.34 (q, J=7, 2H), 3.27 (s, 3H), 1.31 (t, J=7, 3H).

Provenance & Evidence