反应详情

The titled compound was prepared in 90% yield from phenyl isocyanate using the procedure detailed for compound 7. mp 171.0-172.1° C. 1H NMR (300 MHz, DMSO-d6): δ 8.43 (s, 1H), 7.79 (d, J=9 Hz, 2H), 7.47-7.36 (m, 9H), 7.29-7.16 (m, 4H), 6.87 (t, J=7 Hz, 1H), 6.57 (s, 1H), 6.23 (t, J=6 Hz, 1H), 3.25-3.14 (m, 2H), 2.69 (t, J=8 Hz, 2H), 1.92-1.78 (m, 2H). MS (ESI) m/z: 476.18 (M+H+). Anal. Calcd for C25H25N5O3S.0.3CH4O: C, 62.63; H, 5.44; N, 14.43. Found: C, 62.63; H, 5.34; N, 14.41.