HCID 86709972, compound → HCID 67992591, compound

Participants

Reaction Steps

To a solution of 9h (0.4 g, 1.2 mmol) in EtOAc was added 10% palladium on carbon. The solution was filled with H2 and the reaction mixture was stirred for 2 hours. After the solution was filtered through Celite, the filtrate was concentrated in vacuo. Purification by recrystallization with DCM/hexanes gave the title compound 10h, 0.35 g (95%) as a white solid. mp 137.5-145.1° C. 1H NMR (300 MHz, DMSO-d6): δ 8.05 (d, J=8 Hz, 2H), 7.67 (d, J=8 Hz, 2H), 6.27 (s, 1H), 3.62 (s, 2H), 3.32 (s, 3H), 2.07-1.83 (m, 2H), 1.14 (s, 9H).

Provenance & Evidence